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Most drugs are far better absorbed from the first 12 inches of the small intestines called the duodenum, from the Latin word for 12 (duodecum)

Freund Levi Y, et al

391 Recessive POLG mutations can be homozygous or compound heterozygous, with compound heterozygous mutations in trans often associated with a more severe and earlier-onset phenotype, whereas homozygous recessive mutations tend to result in a milder and later-onset presentation

Worsening of seizures after asparagine supplementation in a child with asparagine synthetase deficiency

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