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Bariatric surgery Restricted stomach = reduced B12

While the efficacy data did not survive the Phase IIb primary endpoint, the safety dataset across 900 participants is unusual for a research peptide and is consistently cited as the basis for continued investigational interest

(2019) 43:e12888

In ICH patients, time-adjusted methods did not enhance model performance, possibly due to a smaller sample size and weaker predictive value of time-to-assessment for our outcomes