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The review situates Dihexa within the renin-angiotensin systems central nervous system arm, summarizes the HGF/c-Met activation hypothesis, and surveys behavioral pharmacology in rodent cognitive models

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In a case-control study, supplementation with 20,000 IU vitamin D 2 per day for six weeks resulted in decreased symptoms and improved quality of life in participants with chronic urticaria and vitamin D insufficiency who were also being treated with antihistamines (Boonpiyathad 2014)