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Pregnancies within the first-year post-LT confer the greatest risks to the mother, graft, and infant, thus pregnancy prevention for those who wish to avoid pregnancy is key

Additionally, the prevention of monocyte entry into the optic nerve head through irradiation has been demonstrated to protect against neuronal damage in DBA/2J mice, further illustrating the role of immune cells in neurodegenerative processes (160)

Nobre AC et al

Its mutation can cause the overexpression and aggregation of -syn, resulting in the formation of Lewy bodies

Specifically, TST downregulation leads to decreased S-sulfhydration of very long-chain specific acyl-CoA dehydrogenase (VLCAD), an enzyme essential for mitochondrial FAO