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A quantitative mass-spectrometry platform to monitor changes in cysteine reactivity, in , edsOverkleeftH

Abstract Nicotinamide adenine dinucleotide (NAD) and glutathione are vital molecules that control redox-state, enzyme functions and metabolic flux in hundreds of cellular metabolic reactions

The discovery of 5-FU up-regulation of GPX4 in this study is consistent with the latest reports, and the reproducibility of the results was further confirmed ( Here, we showed that GPX4 inhibition is a promising strategy to selectively eradicate residual CRC cell reservoirs

Engstrm, P

Rothhammer and Quintana, 2019), further implicating its role as a regulatory node, central to maintaining gut homeostasis and a possible biomarker for GI disorders (Obata et al., 2020)