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In intestinal epithelial cells, the activation of toll-like receptors (TLRs) and the recognition of TNF- by these receptors initiate the downstream NF-B signaling pathway

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10.3389/fimmu.2021.734229 [DOI] [PMC free article] [PubMed] [Google Scholar] Carvalho A

Consistent with this finding, we observed that the deficiency of myeloid Cox10 , which encodes the mitochondrial complex IV 121,122,123,124,125 , decreased inflammation, promoted VAT resident macrophage survival, and improved glucose tolerance