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These G protein-coupled receptors (Waldhoer et al., 2004) undergo conformational changes upon heroin binding, thereby inhibiting adenylate cyclase activity, reducing cAMP production (Tedford and Zamponi, 2006), and subsequently impairing neuronal signaling (Figure 3)

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The Confusion Around SPCD and Autism If you have been researching SPCD online, you may have seen articles discussing a link between SPCD and autism