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Description

Parkinsons disease is associated with impaired gut-blood barrier for short-chain fatty acids

Furthermore, this study discovered that the inactivation of DHODH could sensitize GPX4 high cancer cells to ferroptosis inducers, and potentiate ferroptosis in GPX4 low cancer cells

The downregulation was 0.29-fold, 0.22-fold, and 0.16-fold, respectively, compared to the control group ( P 0.05)

Materials and methods Institutional Review Board approval was obtained at the University of Washington for this single-center study of 15 participants with mid-stage PD