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P.FiorileM

Glutathione transferases kappa 1 and kappa 2 localize in peroxisomes and mitochondria, respectively, and are involved in lipid metabolism and respiration in Caenorhabditis elegans

Wuyts, F.L

SIRT1 overexpression mitigates oxidative stress and mitochondrial dysfunction in HEI-OC1 cells exposed to H 2 O 2 The AMPK signaling pathway, which plays a critical role in regulating energy metabolism and oxidative stress responses, appeared to be significantly influenced by SIRT1 in our NIHL mouse model

(4) inter-cellular transmission: HTLV-1 primarily spreads through cell-to-cell contact, particularly by forming virological synapses or multinucleated cells, which transfer the virus from infected to uninfected cells