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DNA damage: Accumulating mutations that impair gene expression

Eckert MA, Coscia F, Chryplewicz A, Chang JW, Hernandez KM, Pan S, Tienda SM, Nahotko DA, Li G, Blaenovi I, Lastra RR, Curtis M, Yamada SD, Perets R, Mcgregor SM, Andrade J, Fiehn O, Moellering RE, Mann M, Lengyel E (2019) Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts

As the body doesnt make B12 or store it for a long time, supplementation may be required for those at risk of deficiency

Many patients experience improved mood, energy, and mental clarity after treatment

There is no official link between standard B12 supplementation and serious adverse effects in individuals with normal kidney and liver function