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Collectively, these results demonstrate that Gepon can activate fibroblasts, though less efficiently than TGF-1, and without stimulating endogenous TGF-1 transcription [2]

Epitalon's chromatin remodeling effect demonstrated in Khavinson's 2003 work on heterochromatin activation in aged cells removes structural barriers to gene expression that would otherwise limit GHK-Cu's transcriptional effects.11 Epitalon opens the chromatin