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J Neuroimmune Pharmacol (2020) 15(1):7481

it can be a sign of skin disease, infection (such as onychomycosis) or tissue injury

European Neuropsychopharmacology, 19(S9), S681S682

This review demonstrates that, acupuncture, as an adjuvant therapy can play a potential important role in the treatment of PSCI by regulating the microbiota-gut-brain-axis (Figure 1)