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In order to further analyze the metabolites in the eight groups, the fold change and p -value of metabolites between the groups were calculated and plotted as volcanoes, as shown in Figures 4B,D,F,H,J,L,N,P

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However, it is crucial to simultaneously focus on improving manufacturing practices, implementing quality control standards, and establishing regulatory oversight to ensure the safety and efficacy of probiotic products in the face of increasing therapeutic applications

Disclosures: Nimmy Thomas: Nothing to Disclose, Christina Stull: Nothing to Disclose, Holli Sadler: Nothing to Disclose 1056 RISK OF INCIDENT EXTRAHEPATIC CANCERS AMONG MEDICARE PATIENTS WITH NON-ALCOHOLIC STEATOHEPATITIS (NASH) Jesse Fishman 1 Yestle Kim 1 Joe Medicis 1 Matthew Davis 2 Dominic Nunag 2 Robert Gish 3 , 1 Madrigal Pharmaceuticals, Inc., 2 Medicus Economics, LLC, 3 Robert G Gish Consultants LLC Background: NASH, or metabolic dysfunction-associated steatohepatitis (MASH), is a severe form of non-alcoholic fatty liver disease (NAFLD), or metabolic dysfunction-associated liver disease (MASLD)

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