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doi:10.1007/bf00329668

It passes through the blood-brain barrier with ease and is welcomed by the brain cells (neurons, microglia, and astrocytes)

Arun Nagdev, MD , is director of the Ultrasound Division at Highland Hospital References Friedman BW, Chilstrom M, Bijur PE, Gallaghar EJ

Doyle TJ, Braun KW, McLean DJ, Wright RW, Griswold MD, Kim KH

Furthermore, PPE is capable of modulating several critical molecular pathways, including mitogen-activated protein kinases, nuclear factor-kappa B (NF-B), cysteine-aspartic acid-specific proteases, and peroxisome proliferator-activated receptors, thus providing theoretical support for its use in the treatment of a variety of diseases (Ganeshkumar et al., 2013