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Macrophages exposed to supernatants from IgE-activated mast cells exhibited increased basal oxygen consumption rates (representative of mitochondrial respiration), ATP production, maximal respiration, and spare respiratory capacity compared to cells exposed to supernatants from non-sensitized mast cells

M2 macrophages lacking Atg5 exhibit a proinflammatory transformation to M1-like phenotype characterized by elevated production of TNF- and IL-6

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