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Back to Journals Journal of Blood Medicine Volume 16 Multifaceted Clinical Spectrum of Vitamin B12 Deficiency - a Case Report and Literature Review Authors Pustelnik E , Pikora K, Hartman MZ, Kurzeja M, Czuwara J, aguna P Received 28 February 2025 Accepted for publication 7 July 2025 Published 25 August 2025 Volume 2025:16 Pages 391411 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Martin H Bluth Ewa Pustelnik, 1, * Katarzyna Pikora, 1, * Magdalena Zofia Hartman, 2 Marta Kurzeja, 3 Joanna Czuwara, 3 Pawe aguna 1 1 Department of Oncology, Pediatric Hematology, Clinical Transplantology and Pediatrics, Medical University of Warsaw, Warsaw, Poland

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This reduces the elasticity and firmness of the skin, leading to the formation of wrinkles and loss of facial definition