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(iv) glutamine polarizes macrophages to M2 phenotype [183] and, as a precursor of glutamate, can also restrain macrophages function, after glutamate-induced N-methyl-D-aspartate receptor (NMDAR) channel activation, leading to tumor development in mouse models of fibrosarcoma and hepatocellular carcinoma [184]

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10.1016/j.bioorg.2025.108226 51 GhavamiS.ShojaeiS.YeganehB.AndeS.-R.JangamreddyJ.-R.MehrpourM.et al (2014)

I dont think most people who are prescribed them should take them, but I think that its a worse malfeasance to be putting kids on them