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Conclusions We provide initial evidence from in vitro and in vivo models indicating that n-3 polyunsaturated fatty acid (PUFA) supplementation could help reduce toxicity

Briefly, separation was carried out using a nano-ACQUITY Ultra Performance LC Chromatography System (Waters Corporation, Milford, MA, USA) with a nano-Acquity UPLC BEH130 C18 RP column and an enrichment Symmetry C18 RP column

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About the study In the current study, researchers investigate how alterations in TrkB signaling in iSPNs and changes in the metabolism of glutathione could impact dopamine levels, progressive neuronal degeneration, and the onset of motor dysfunction in Huntingtons disease

Yet, enthusiasm generated from bench to mouse has not been matched by confirmatory evidence from ward to wallet