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As discussed in Sect

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TripathiALammersKMGoldblumSShea-DonohueTNetzel-ArnettSBuzzaMSet al

Infusion duration at this dosage often ranges from two to three hours

It is well known that, glucose metabolism is reprogrammed during tumorigenesis for a rapid growth and survival, so tumor cells switch to glycolysis instead of oxidative phosphorylation (OXPHOS) [51]