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In addition to the problem of vaping leading to smoking, the Pediatrics study found that the volatile chemicals in e-cigarettes, like propylene glycol and glycerol, can form carcinogenic compounds when heated, and that those compounds were found in the urine of the 16 year olds who were tested

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The two estimates are not wholly comparable because of the difference in age at recruitment and the stage at which smoking status was recorded but are sufficiently similar to suggest the validity of the findings of this study