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10.1016/j.taap.2017.08.003 47 CetinM

the invention provides a method of modulating the expression of a polypeptide by a cell, comprising providing to a cell a lipid particle that consists of or consists essentially of a cationic lipid of formula I, a neutral lipid, a sterol, a PEG of PEG-modified lipid, e.g., in a molar ratio of about 20-65% of cationic lipid of formula I, 3-25% of the neutral lipid, 15-55% of the sterol, and 0.5-15% of the PEG or PEG-modified lipid, wherein the lipid particle is associated with a nucleic acid capable of modulating the expression of the polypeptide

D., Maratou, E., Kountouri, A., Board, M

Common timing: morning fasted, pre-workout, and before bed