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Neurological symptoms (tingling, balance issues) take longer, typically three to six months, and in some cases longer if deficiency was long-standing before supplementation began

Together these data support the proposed mechanism that dihexa facilitates dimerization of HGF that subsequently activates the MET receptor and, subsequently, downstream intracellular signaling pathways 22

No effects were observed in Wistar rats exposed to a lower concentration, 5 days/week for 4 weeks, either as a "continuous" (6 h/day) exposure of 270 mg/m 3 , or as a time-weighted average of 255 mg/m 3 after the described intermittent low-high exposure

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Virtual: National Bureau of Economic Research