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Protein expression in insect cells Spodoptera frugiperda (Sf9) cells (Thermo Fisher Scientific) were cultured in Graces Insect Cell Culture Medium containing 10% fetal bovine serum (Thermo Fisher Scientific) and shaken at 120 rpm at 27 C in a humidified incubator

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The research findings suggest arginine degrading enzymes may have synergistic effects with many other pathway inhibitors in treating arginine-auxotrophic cancers

This is attributable to the presence of a highly activated carbon atom in the heptadienone linkage between the two-methoxy phenol rings of bis-keto form of curcumin

Additionally, an imbalance in metal ions can contribute to the development of neurodegenerative diseases through a variety of mechanisms, including promoting the production and aggregation of pathological proteins, inducing oxidative stress, ferroptosis, cuproptosis, cell senescence, or neuroinflammation