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The exact relationship of Vit D and PD remains unclear, given controversial findings with vitamin D supplementation not always impacting the clinical manifestation or the level of disability in PD (Pignolo et al

But beneath the surface of glossy marketing and fitness fantasies lies a far more sobering truth: many of these substances operate in a medical grey zone, with unknown long-term risks, questionable manufacturing standards, and in some cases, life-threatening side-effects

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Calcitriol can affect neuroplasticity, apoptosis, and gene expression (such as neurotransmitters, neurotrophic, and synaptic proteins) (102)

Int J Urol 2013