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[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Venkatesan P

Apc-mutated intestinal tumors lacking Stard7 are sensitive to mTORC1 inhibition Given the fact that intestinal tumors arising from constitutive Wnt signaling and lacking Stard7 show enhanced mTORC1 signaling, we hypothesized that these malignancies would be very sensitive to mTORC1 pharmacological inhibition

As the body ages, natural antioxidant production declines

We used a high-throughput, phenotypic screening in Caenorhabditis elegans to search for compounds that increased accumulation of a GFP-tagged C

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