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Given their similarities, the choice between these methods should be guided by research objectives and practical factors, including expenses, resource availability

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Furthermore, these models are constructed based on predetermined assumptions as well as patterns derived from existing data, which may potentially overlook other essential factors and underlying mechanisms

Microbial fermentation and enzymatic hydrolysis are the most favorable biotechnological methods to treat animal waste proteins to decode bioactive peptides from parental proteins, especially enzymatic hydrolysis, which is more efficient at producing the peptide with a specific activity and more used in finding novel bioactive peptides in animal waste proteins, than microbial fermentation

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