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The animal studies used both local application at the injury site and systemic administration (intraperitoneal and intragastric), with both routes showing significant effects

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Role in Angiogenesis & Inflammation Angiogenesis, the formation of new blood vessels, is vital for nutrient and oxygen delivery to healing tissues

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However, users recovering from long-term or severe injuries may choose to reduce dosing graduallyfor example: Week 14: 500mcg/day Week 5: 250mcg/day Week 6: 250mcg every other day This mild tapering strategy may help the body normalize while preserving healing momentum, especially when transitioning into maintenance supplements like collagen, MSM, or glutathione