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Auto-Oxidative Damage in Cement Dermatitis

PMID 16436974

Despite our observation that CAR loss-of-function during sepsis leads to the downregulation of various hepatic metabolic genes, including those involved in the metabolism of bile acids and fatty acids, as well as genes from the TCA cycle, additional metabolic data, such as the measurement of bile acids and bilirubin, would further strengthen these findings

36 Ferric ions are then released from the transferrin complex by endosomal acidification and reduced to ferrous ions (Fe 2+ ) by six-transmembrane epithelial antigen of prostate 3 (STEAP3), Tf will separate from its receptor TfR1 and re-enter the bloodstream to capture ferric ions