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While there is no exact definition for B12 levels, a normal B12 serum test level is considered around 300-900pg/mL, while deficiency is less than 200 pg/mL

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The Methylcobalamin version of B12 helps reduce homocysteine concentration by converting homocysteine to methionine through a methylation process

It has a positive effect in preventing many diseases, such as cancer, Parkinsons disease and cardiovascular diseases

- when there is risk of torsades de pointes, for example in patients with prolonged QT, concomitant administration of other medications that produce torsades de pointes (amiodarone, quinidine, bepridil, IV erythromycin, halofrantine, pentamidine, sparfloxacin, sultopride, vincamine, betrilio, disopyramide, sotalol, etc)