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217,218,219 Intriguingly, accumulating studies have revealed the key role of lactylation in cancer epigenetic rewiring (Fig

[Para 27] 3

Semaglutide 2.4mg (GLP-1 Agonist): Proven GLP-1 effects (appetite suppression, gastric emptying) Already FDA-approved as Wegovy Established safety profile Cagrilintide 2.4mg (Amylin Analog): Mimics amylin, a hormone co-secreted with insulin Slows gastric emptying through different pathway than GLP-1 Reduces appetite through hindbrain (not hypothalamus) Improves postprandial glucose The Advantage: Leverages proven semaglutide efficacy and safety, adds complementary amylin effects

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As people age, their bodies often become less efficient at absorbing and metabolizing nutrients due to changes in gastrointestinal function, such as decreased stomach acid production or altered gut flora