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It has been known for several years that it is extremely difficult to lose weight once obesity has set in, which means that we must take a proactive approach with children and adolescents, before they accumulate excess weight that exposes them to a very high risk of obesity in adulthood (more than 80% of obese adults were already obese during their childhood)

These novel insights into the crosstalk of two major pathogenic pathways in glioblastoma may explain some of the disappointing results when targeting either pathway alone in human glioblastoma patients and inform on potential future designs on targeted pharmacological or genetic intervention

Mendez-Sanchez N, Gonzalez V, Aguayo P, Sanchez JM, Tanimoto MA, Elizondo J, Uribe M

G., Copits, B

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