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Description

Activated T cells express FasL, which binds to FasR on the target cell surface, recruiting FADD to the cytoplasmic side and activating caspase 8, thereby initiating the apoptosis cascade and triggering cell death

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Since COX-2 was found to be underexpressed, inadequate COX-2 regulation may also be involved in the pathogenesis of AEA

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HSPs and autophagy: a synergistic relationship HSPs, particularly HSP70 and HSP90, play a pivotal role in protein folding and refolding, preventing the aggregation of misfolded proteins

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