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The administration of Nigella sativa and Nigella sativa-mediated AgNPs demonstrated a reduction in toxicity

To balance the redox state and intracellular iron homeostasis, excess intracellular Fe 2+ can be translocated out of the cell via the carrier SLC40A1 (73, 74)

dAGEs intake induced intestinal barrier dysfunction and dysbiosis of the gut commensal consortium An increased intestinal permeability and compromised mucosal barriers predispose to allergic and autoimmune disorders 28,30

BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies