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In rabbit models, intra-articular injection of scAAV2 encoding interleukin-1 receptor antagonist (IL-1Ra) yielded sustained therapeutic protein expression in both inflamed and normal joints for at least two weeks, with minimal immune activation or joint pathology (178)

Clinical studies on DNA methylation-based biomarkers in cancer diagnosis and prognosis Over the last few decades, an increasing number of observational clinical studies have been initiated to validate DNA methylation hotspots as cancer-specific biomarkers in real-world clinical settings

Saneja A, Arora D, Kumar R, Dubey RD, Panda AK, Gupta PN

Conclusion: There is a significant discrepancy between explant and pre-LT imaging in HCC LT recipients

Bedogni F, Hodge RD, Elsen GE, Nelson BR, Daza RA, Beyer RP, et al