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A post-RYGB patient with serum B12 below 100 pmol/L may need eight to twelve weeks of aggressive repletion, sometimes with intramuscular injections, before I am comfortable operating

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This means they are a much richer source of sulforaphane when eaten raw or lightly steamed, as cooking can destroy the enzyme myrosinase needed for conversion

This kind of trial is expensive typically several million dollars and to date has been more difficult to justify economically because GHK-Cu cannot be patented as a novel drug (the molecule is endogenous and the relevant patents have expired)