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A.Lugo-LugoO.et al

The higher levels of ROS can also be caused by oncogenes such as constitutively active isoforms of RAS , and oncogenic K-RAS have been found to be necessary for precancerous lesions in the pancreas and for lung adenocarcinoma formation [35,36]

12 However, the lack of a control groups in both of these studies and combination topical cream containing other active ingredients makes it impossible to attribute these benefits solely to glutathiones antioxidant effect alone