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The coccidia eggs (oocytes) can pass from an adult goat in feces and get into contaminated food and water, where younger goats can easily get it and get infected by the coccidia

In fibroblast cultures, it has been shown to modulate expression of a large number of genes involved in repair and antioxidant defense

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For patients with complex chronic illnesses who often already suffer from irritable bowel syndrome (IBS), mast cell activation syndrome (MCAS), or general gut sensitivity, this laxative effect is entirely counterproductive and can lead to further dehydration and electrolyte imbalance

These data suggest that downregulation is not mandatory for tolerance