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Its most significant and well-understood roles are: Collagen synthesis: Vitamin C is an essential co-factor for the enzymes prolyl hydroxylase and lysyl hydroxylase, which are required to stabilise the triple-helix structure of collagen fibres

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The researchers showed that senescent Leydig cell accumulation is a driver of age-related testosterone decline, and that targeted elimination of these cells with FOXO4-DRI restored endocrine function

Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis

For example, the families Bacteroidaceae, Enterococcaceae, and Lactobacillaceae are more common in the intestinal lumen, while the families Lachnospiraceae, Ruminococcaceae are more common in the mucosa ( In general, commensal microorganisms participate in host digestion, biosynthesis of vitamins, production of short-chain fatty acids (SCFAs) and bacteriocins, development of the hosts immune system, and functioning of the gut-brain axis