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Chemotherapy with drugs like 5-fluorouracil has also been associated with acute thiamine deficiency by disrupting thiamine activation, so oncology patients receiving such therapy might receive parenteral thiamine supplementation as part of this B-Complex if needed

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Genetic factors: In rare cases, PA can be genetic

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Norris recommends vegan adults 18 to 65 years old should take one of the following regimens: two doses per day of 2 to 3.5 mcg per serving, one dose per day of 25 to 100 mcg per serving, or two doses per week of 1,000 mcg per serving