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These assay systems should prove useful is the ongoing assessment of the ability of such reagents to increase cell resistance to damage by HD.

Differential response of methionine metabolism in two grain legumes, soybean and azuki bean, expressing a mutated form of Arabidopsis cystathionine gamma-synthase

Steroid production in the skin is directly dependent on local enzymatic activity (e.g., aromatase), substrate availability, and mobilization of signal transduction and gene expression pathways, and can be modulated by several internal and external factors, including growth factors, inflammatory cytokines such as IL-1 and TNF, cAMP analogs, and glucocorticoids such as dexamethasone (Tkachenko et al., 2011

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Chemical modification of a specific inhibitor of nicotinamide N-methyltransferase to generate a membrane-permeable prodrug. Journal of Medicinal Chemistry , 61(3), 1366-1371