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An increased ROS and MDA levels were observed with a subsequent decrease in thiol levels, CAT, and glutathione-S-transferase activities (129)

Selenium metabolism pathways

J., Xu, D., Poole, D., Grand, S

In fact, increased utilization of glucose by the glycolytic pathway and not by the pentose phosphate pathway (PPP), together with a decrease in the levels of transketolase transcripts (PF3D7_0610800) of PPP ( Thus far, all the changes proposed agree with an increase of oxidative stress tolerance in some resistant strains compared with sensible ones

Yes, sun protection remains essential regardless of any skin treatment, as UV exposure is a major factor in pigmentation and skin dullness