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Samples were centrifuged at 13,000 rpm for 20 min at 4 C

A systematic bibliometric analysis revealed that research on natural products for DKD treatment has grown exponentially in recent years, with research hotspots primarily focusing on oxidative stress, inflammatory responses, gut microbiota regulation, and podocyte protection (22)

Individuals with liver or kidney concerns, or those planning surgery, discuss with a healthcare provider before use

The most common inciting drugs are allopurinol, antibiotics (particularly sulfonamide antibiotics), antiepileptics, and NSAIDs

When levothyroxine is used at the appropriate dose, no significant side effects are expected It is a low-cost medicine