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While the anti-inflammatory and neuroprotective effects of PEVs are clear in our two models of brain pathology, comprehensive evaluation in long-term pre-clinical models is still required

It has been proposed that oxidative stress-related diseases can be cured by the enhanced supply of antioxidants

[ref][ref] However, the lack of change in autonomic function due to a specific chemical may not be the right variable to control for

Latter study also identified genes related to iron metabolism (TFRC) and glycolysis (PGK1), in line with VitC-induced changes on the protein level observed in the proteomic studies referred to before [159, 160]

Effects of mitochondrial dysfunction via AMPK/PGC-1 signal pathway on pathogenic mechanism of diabetic peripheral neuropathy and the protective effects of Chinese medicine