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Plasma lipid-profile measurements showed that the total cholesterol levels were 30% lower in treated DIO mice relative to control DIO mice (P 0.05

showed a correlation between lower B12 levels and a lower age at MS onset

This cysteine-homocysteinylation event perturbs the pro-insulin receptor and furin protease interaction within the Golgi apparatus, consequently inhibiting the cleavage of the pro-insulin receptor