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Thus, glutamatergic dysfunction in schizophrenia is certainly associated to metabolic impairments

Nat Rev Microbiol 21 , 555572 (2023)

Even if the exact conversion mechanism has not been characterised yet, a limited conversion capacity in Western populations (about 25 %) has been highlighted, as opposed to the greater competence of Asian populations (50 %), estimated through urinary equol excretion (Reference Setchell, Brown and Lydeking-Olsen17)

Folate testing, either serum folate or red cell folate, was done in a small minority of patients in this study, and only one patient was identified with possible deficiency

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