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Ethics declarations Competing interests The authors declare no competing interests that could have appeared to influence the work reported in this paper

In these models, evodiaminemediated reduction in lactatelinked histone lactylation suggests its ability to intersect metabolic and epigenetic regulation in pathological states driven by enhanced glycolysis and lactate accumulation [67]

Premium seasonal fruits, vegetables and seaweeds are added in as prebiotics for good bacterias' growth

Their microbiological status was examined as recommended by the Federation of European Laboratory Animal Science Associations and the mice were free of all listed pathogens