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Heterozygous carriers of the mutant FXN gene have 50% lower frataxin levels, but this decrease is not enough to cause symptoms

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The cows were fed a partial mixed ration according to the guidelines of the Society of Nutritional Physiology (GfE, 2001) for nutrient and energy supply, consisting of 50% roughage (70% maize silage and 30% grass silage) administered in feed-weigh troughs (Roughage Intake Control, System Insentec B.V., Marknesse, The Netherlands) and 50% concentrate feed, administered in electronic feeding stations (Insentec B.V., Marknesse, The Netherlands)

Creatine: 5 grams per day of monohydrate