While it is used in skincare, it is generally more focused on scalp and hair care than GHK-Cu[1]
Key Research Areas Extracellular matrix remodelling GHK-Cu is extensively referenced in studies on collagen, elastin, and glycosaminoglycan synthesis in laboratory tissue models Wound healing mechanisms Investigated in controlled studies for its role in fibroblast activation, keratinocyte migration, and angiogenesis signalling Anti-inflammatory pathways Studied for inhibition of NF-B signalling and reduction of pro-inflammatory cytokine expression in cell culture Antioxidant activity Research has examined its capacity to upregulate superoxide dismutase and other endogenous antioxidant enzymes Nerve and tissue regeneration Referenced in studies exploring nerve growth factor (NGF) expression and axonal regeneration in vitro Hair follicle biology Investigated for effects on dermal papilla cell proliferation and follicle stimulation in skin research models Gene expression modulation Genome-wide studies have identified GHK-Cu as a potential modulator of over 4,000 human genes associated with tissue repair and inflammatory response Product Specifications About the Compound GHK-Cu is a tripeptide (Gly-His-Lys) with a high affinity for copper ions (Cu), forming a stable complex that has demonstrated significant biological activity across hundreds of peer-reviewed studies
Cryo-EM data for the wt PV2-CP17 complex were collected at 300 kV on a Titan Krios (Thermo Fisher Scientific) equipped with a K3 DED and GIF Quantum energy filter (Gatan) at the electron Bio-Imaging Centre, Diamond Light Source, UK
Heliyon 10(14):e34269 Yao Y, Yuan Y, Lu Z, Ma Y, Xie Y, Wang M, Liu F, Zhu C, Lin C (2021) Effects of Nervilia fordii extract on pulmonary fibrosis through TGF-/Smad signaling pathway
Glycyl-histidyl-lysine (GHK) is a quencher of , -4-hydroxy-trans-2-nonenal: a comparison with carnosine
