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cAMP/PKA Steroidogenic Signalling In primary mouse Leydig cell cultures, hCG was found to be approximately 10-fold more potent than LH in cAMP recruitment, and slightly but significantly more potent in cAMP-dependent Erk1/2 phosphorylation though no significant differences were observed at the level of downstream steroidogenic events including Creb phosphorylation, Stard1 gene expression, and testosterone synthesis

Other reports have suggested that arsenic may induce lipodystrophy [193]