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doi: 10.1016/j.nut.2020.111023 120

This is one of the first studies suggesting that TBK1 mediated S403 phosphorylation regulates autophagosomal engulfment of ubiquitinated mitochondria as an immediate response to the mitochondrial depolarization under neurodegeneration

Loading Phase Option Some protocols recommend 8mg daily for the first two weeks (5 days on, 2 days off), followed by 4mg daily for 10 weeks using the same schedule